A good clinical question has five principal elements. These elements include Patient/Problem, Intervention, Comparison, Outcome, and Time/Type of Question/Type of Study. In the absence of an accurately developed clinical question, researching relevant evidence can become difficult and overly time-consuming. PICOT, also known as PICO, is a specialized framework that supports you as you formulate your clinical question. PICOT helps you find the most valuable information from the latest research. Evidence-based nursing relies heavily on PICOT. And evidence-based nursing is slowing but surely becoming the standard in most healthcare settings. We wrote this page to help you understand that writing PICOT nursing questions isn’t exactly rocket science.